Targeting Beyond the Liver – Achieving Organ-Specific Delivery with Next- Generation Lipid Libraries, Formulations & Payload Optimizations

  • How can we improve lipid nanoparticle design for organ-specific delivery to expand the therapeutic range of LNPs?
  • Unleashing AI-assisted and machine learning capabilities to screen novel lipids with distinct organ tropism, enhancing efficacy while reducing toxicity to broaden the dosing window
  • Assessing current LNP engineering strategies and library designs for optimal screening and effective extra-hepatic targeting