From Cap to Tail: Applying Holistic Design Strategies to Accelerate mRNA Discovery

  • Advancing mRNA therapeutics requires an integrated approach that unites smart design with chemical innovation
  • Exploring how TriLink’s next-generation solutions accelerate mRNA discovery by combining AI-driven UTR optimization, ModTail™ poly(A) tail modification, and CleanCap® M6 technology for prolonged expression and enhanced translational efficiency
  • Together with TriLink’s novel design platform, mRNAbuilder, these tools enable data-informed, end-to-end optimization of mRNA architecture—transforming how researchers design, test, and refine transcripts for superior therapeutic performance